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Antimicrobials: Antibiotics, Antivirals, AntiProtozoals, Antiparasitics

RITHCLAR™ 500

Clarithromycin 500 mg

Dosage Form Tablets
Packing 10*10 BLI
MRP Max DPCO
Prescribed By Pulmonologist, ENT Specialist, Dermatologist, General Physician, Internal Medicine

Quick Facts

Half Life 3–7 hours; Bioavailability: ~55%; Storage: Below 30°C; Schedule: H; DPCO: Yes; 2-Year Expiry

Key Benefits

01
Guideline-dose for H. pylori eradication — the 500mg dose is the standard for all recommended triple therapy regimens
02
MAC prophylaxis and treatment — essential for HIV/AIDS management with CD4 below 50
03
Moderate-severe respiratory infections — higher dose for COPD exacerbations requiring more aggressive macrolide cover
04
DPCO-regulated — critical for long-term MAC treatment affordability
05
Yellow Abbott-type tablet — consistent brand identity across the RITHCLAR™ range
06
2-year expiry — extended shelf life for stocking efficiency

Mechanism of Action

Clarithromycin 500mg — same mechanism as RITHCLAR™ 250 (macrolide, 50S ribosomal binding, translocation inhibition). The 500mg dose is required for moderate-to-severe infections, H. pylori eradication regimens, and MAC prophylaxis and treatment where standard guidelines specify the higher dose. See RITHCLAR™ 250 for full mechanism detail.

Indications

Moderate-to-severe community-acquired pneumonia (combination with beta-lactam), H. pylori eradication (500mg + amoxycillin 1g + PPI twice daily for 14 days), Mycobacterium avium complex prophylaxis (500mg twice daily in HIV patients CD4 <50), severe acute exacerbations of chronic bronchitis, and complicated skin infections where higher macrolide concentrations are needed.

Dosage & Administration

Dosage and administration should be as prescribed by a qualified doctor or medical professional. Do not self-medicate. Always follow your physician's instructions regarding dose, frequency and duration of treatment.

Why RITHCLAR™ 500?

RITHCLAR™ 500 completes the clarithromycin range alongside RITHCLAR™ 250. The 500mg dose is non-negotiable for H. pylori eradication — studies consistently show that 250mg-based triple therapy achieves lower eradication rates than 500mg regimens. Having both strengths under a single brand ensures prescribers can select the appropriate dose for each indication while remaining within the Seclis Labs portfolio.

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Disclaimer: To be used under medical supervision only. Not intended for general public promotion. This content is meant for registered healthcare professionals only.

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