D-VIEW 60K

Vitamin D3 (Cholecalciferol) 60,000 IU oral solution provides a high-dose weekly or biweekly supplementation format for correcting vitamin D deficiency — the most prevalent nutritional deficiency in India, affecting an estimated 70–90% of the population across all demographic groups.

Cholecalciferol (D3) is the natural form of vitamin D synthesised in the skin upon UV-B radiation exposure. After oral absorption, D3 undergoes two sequential hydroxylation steps: first in the liver (producing 25-hydroxyvitamin D — calcidiol, the measurable storage form) and then in the kidney (producing 1,25-dihydroxyvitamin D — calcitriol, the active hormonal form). Calcitriol exerts its biological effects by binding to the Vitamin D Receptor (VDR) — a nuclear receptor present in virtually every cell type in the body, reflecting vitamin D's systemic hormonal role beyond its classical calcium-phosphorus metabolism functions.

Classical Functions of Calcitriol: Stimulates intestinal calcium and phosphorus absorption (increasing calcium absorption from 10–15% to 30–40%), enhances renal calcium reabsorption, stimulates osteoclast-mediated bone resorption (for calcium mobilisation), and promotes osteoblast activity — maintaining bone mineral density and preventing rickets (children) and osteomalacia/osteoporosis (adults).

Non-Classical Functions (now well-established): Immunomodulation (VDR signalling in T-cells, B-cells, and macrophages reduces autoimmune activity and enhances anti-infective immunity), cardiovascular protection (reduces renin expression, lowers blood pressure), insulin secretion (VDR in pancreatic beta-cells), muscle function (reduced falls and improved grip strength), and anti-cancer effects (cell cycle regulation, apoptosis induction).

At 60,000 IU per 5mL nano shot, D-VIEW 60K provides the standard weekly high-dose loading protocol used across India for rapid correction of vitamin D deficiency — a single 5mL dose (60,000 IU) taken weekly for 8 weeks, followed by monthly maintenance.

Vitamin D Deficiency Correction (Primary): Serum 25-OH vitamin D below 20 ng/mL — the most common nutritional deficiency diagnosis in India. The 60,000 IU weekly dose protocol achieves deficiency correction in 8 weeks (target >30 ng/mL) with high patient compliance from the once-weekly regimen.

Rickets Prevention and Treatment: Vitamin D-deficiency rickets in children — high-dose D3 is the treatment of choice alongside calcium supplementation.

Osteoporosis and Osteopenia: Adjunct to bisphosphonate or other anti-resorptive therapy — vitamin D sufficiency is essential for bisphosphonate efficacy (adequate calcium absorption requires normal D3 status).

Post-Menopausal Women: Fracture prevention through bone density maintenance — vitamin D + calcium is the foundational intervention.

Pregnancy and Lactation: Prevention of maternal vitamin D deficiency and foetal/infant bone development — gynecologists routinely prescribe D3 60,000 IU weekly in the second and third trimester.

Immune System Support: Vitamin D's immunomodulatory function makes supplementation relevant for recurrent respiratory infections, autoimmune conditions, and general immune health — supported by growing evidence in infectious disease management.

Chronic Disease Associations: Type 2 diabetes risk reduction, hypertension management, and depression — emerging evidence supporting vitamin D optimisation in metabolic syndrome management.

Dosage and administration should be as prescribed by a qualified doctor or medical professional. Do not self-medicate. Always follow your physician's instructions regarding dose, frequency and duration of treatment.