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Gastrointestinal & Hepatic Therapy

ESODRIFT DSR

Esomeprazole 40mg + Domperidone 30mg SR

Dosage Form Capsules
Packing 10*10 ALU
MRP ₹1400
Prescribed By Gastroenterologist, Internal Medicine, General Medicine, Family Medicine, Surgery

Quick Facts

Esomeprazole 40mg (S-isomer, bioavailability ~89%) + Domperidone 30mg SR; Storage Below 30°C, Alu-Alu; Schedule: H; MRP: ₹1400; Take 30–60 min before breakfast

Key Benefits

01
Esomeprazole's isomeric purity — higher bioavailability than racemic omeprazole, providing more predictable and potent acid suppression
02
40mg dose for severe GORD — superior acid suppression for erosive oesophagitis healing
03
SR domperidone pairing — 12-hour prokinetic complement to esomeprazole's 24-hour acid suppression
04
Alu-Alu packaging — moisture protection for precision dual-release capsule technology
05
Well-established esomeprazole safety profile — extensive global post-marketing data

Mechanism of Action

Esomeprazole 40mg (the S-isomer of omeprazole, with higher bioavailability ~89% versus omeprazole's ~35%, providing more consistent and potent acid suppression) + Domperidone 30mg SR (peripheral D2 antagonist prokinetic, 12-hour sustained release). Esomeprazole's isomeric purity eliminates the R-omeprazole inactive isomer, delivering the full pharmacological dose of active PPI compound — achieving superior intragastric pH control compared to racemic omeprazole 40mg.

Indications

Erosive oesophagitis, severe GORD, functional dyspepsia with significant acid component, H. pylori eradication (PPI component at 40mg for maximum pH elevation and antibiotic efficacy), peptic ulcer healing, and gastroparesis with GORD. The 40mg esomeprazole dose is reserved for moderate-to-severe acid conditions requiring stronger suppression than 20mg formulations.

Dosage & Administration

Dosage and administration should be as prescribed by a qualified doctor or medical professional. Do not self-medicate. Always follow your physician's instructions regarding dose, frequency and duration of treatment.

Why ESODRIFT DSR?

Esomeprazole-domperidone DSR fills the 40mg esomeprazole prokinetic-PPI niche in the ESODRIFT™ range, providing the stronger acid suppression of the established S-isomer PPI with sustained prokinetic cover for patients requiring higher-intensity upper GI symptom management.

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Disclaimer: To be used under medical supervision only. Not intended for general public promotion. This content is meant for registered healthcare professionals only.

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