ESODRIFT LS

Esomeprazole 40mg (ER) + Levosulpiride 75mg (SR)

Dosage Form Capsules

Packing 10*10 ALU

MRP ₹2100

Prescribed By Gastroenterologist, Internal Medicine, General Medicine, Family Medicine, Surgery

Quick Facts

Esomeprazole 40mg ER + Levosulpiride 75mg SR; Storage Below 30°C, Alu-Alu; Schedule: H; MRP: ₹2100; Take 30–60 min before breakfast; Do not crush

Key Benefits

Esomeprazole 40mg ER — highest-bioavailability PPI at double dose for severe acid conditions

Levosulpiride 75mg SR — full sustained prokinetic dose for comprehensive gastroparesis management

Dual ER/SR technology — both components with extended release for sustained dual-mechanism coverage

Levosulpiride psychiatric benefit — mild D2 central activity beneficial in functional dyspepsia with comorbid mood disorder

Premium Alu-Alu — essential for high-technology dual-release pellet capsule protection

Mechanism of Action

Esomeprazole 40mg ER (S-isomer PPI with ~89% bioavailability, superior acid suppression over racemic omeprazole) + Levosulpiride 75mg SR (peripheral D2 antagonist prokinetic, 12-hour sustained release). Extended-release esomeprazole paired with sustained-release levosulpiride — both components releasing over extended periods for maximum coverage of the post-prandial acid and motility dysfunction period.

Indications

Severe GORD with gastroparesis, erosive oesophagitis with delayed gastric emptying, diabetic gastroparesis with concurrent reflux, functional dyspepsia requiring potent acid suppression combined with prokinetic therapy. Preferred over ESODRIFT DSR (domperidone combination) when levosulpiride's mild psychiatric D2 benefit (dysthymia, functional dyspepsia with anxiety overlay) is clinically relevant.

Dosage & Administration

Dosage and administration should be as prescribed by a qualified doctor or medical professional. Do not self-medicate. Always follow your physician's instructions regarding dose, frequency and duration of treatment.

Why ESODRIFT LS?

ESODRIFT LS completes the ESODRIFT™ range alongside ESODRIFT DSR — providing the levosulpiride prokinetic option for gastroenterologists who prefer levosulpiride over domperidone for their GORD + gastroparesis patients. The ESODRIFT™ brand covers both prokinetic options (domperidone and levosulpiride) with esomeprazole 40mg as the common acid-suppressive backbone.

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Disclaimer: To be used under medical supervision only. Not intended for general public promotion. This content is meant for registered healthcare professionals only.