NAPWAY D

Quick Facts

Naproxen 500mg + Domperidone 10mg; Half Life Naproxen 12–17h; Storage: Below 30°C; Schedule: H; Take with food; Avoid in peptic ulcer disease without gastroprotection

Key Benefits

01

Full adult anti-inflammatory naproxen dose — 500mg achieves optimal articular tissue drug concentrations for moderate-to-severe musculoskeletal conditions

02

Twice-daily convenience — naproxen's 12–17h half-life enables twice-daily dosing for arthritis management

03

Domperidone gastroprotection and anti-emetic — reduces NSAID GI side effects and enables oral completion in nauseated patients

04

Migraine standard dose — 500mg naproxen is the primary acute migraine NSAID dose in international guidelines

05

Orthopedic-rheumatology specialist appeal — positioned for the highest-volume arthritis and sports injury prescribing market

Mechanism of Action

Naproxen 500mg (standard adult therapeutic NSAID dose, COX-1/COX-2 inhibition, 12–17 hour half-life) + Domperidone 10mg (peripheral D2 prokinetic/anti-emetic). At 500mg, naproxen achieves full anti-inflammatory concentrations appropriate for moderate-to-severe musculoskeletal and articular pain. Domperidone reduces NSAID-associated nausea and facilitates naproxen absorption in conditions with gastroparesis or migraine-associated gastric stasis. See NAPWAY D 250 for full mechanism detail.

Indications

Primary indication for orthopedics and rheumatology: osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, gout (acute attack), low back pain, soft tissue injuries, post-operative pain, and dental pain. The 500mg dose provides optimal anti-inflammatory concentrations for moderate-to-severe articular and musculoskeletal pain. Migraine — 500mg naproxen is the primary guideline dose for acute migraine with domperidone for nausea.

Dosage & Administration

Dosage and administration should be as prescribed by a qualified doctor or medical professional. Do not self-medicate. Always follow your physician's instructions regarding dose, frequency and duration of treatment.

Why NAPWAY D?

NAPWAY D 500mg is the flagship orthopedic NSAID product of the NAPWAY D™ range — providing the standard full adult naproxen dose for arthritis and musculoskeletal pain with the added tolerability and anti-emetic benefit of domperidone. For rheumatologists managing arthritis patients on long-term NSAID therapy, the domperidone component helps maintain compliance by reducing the nausea and GI discomfort that frequently cause premature NSAID discontinuation.