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Antimicrobials: Antibiotics, Antivirals, AntiProtozoals, Antiparasitics

OFLOFT™ MS

Ofloxacin 50 mg + Metronidazole 120 mg + Simethicone 10 mg

Dosage Form Suspension
Packing 60 ml with Carton
MRP ₹95
Prescribed By Pediatrician, Gastroenterologist, General Physician, Internal Medicine, Family Medicine

Quick Facts

Concentration Ofloxacin 50mg + Metronidazole 120mg + Simethicone 10mg per 5mL
Storage Store below 30°C, protect from light
Schedule H
Route Oral suspension
Avoid Alcohol during therapy (disulfiram-like reaction with metronidazole)

Key Benefits

01
Triple-action formulation — fluoroquinolone + nitroimidazole + anti-flatulence in a single suspension
02
Covers both aerobic and anaerobic/protozoal gastrointestinal pathogens comprehensively
03
Simethicone provides symptomatic gas and bloating relief alongside antimicrobial treatment
04
Convenient suspension format for paediatric and adult patients
05
60mL bottle adequate for a full 5–7 day treatment course
06
Affordable ₹95 MRP for broad market access

Mechanism of Action

Triple-component paediatric suspension targeting gastrointestinal infections. Ofloxacin (50mg/5mL) inhibits DNA gyrase and topoisomerase IV, covering aerobic gram-negative enteric pathogens including E. coli, Shigella, and Salmonella. Metronidazole (120mg/5mL) is a nitroimidazole that generates reactive nitrogen intermediates inside anaerobic and microaerophilic organisms, causing lethal DNA strand breaks — specifically targeting Giardia lamblia, Entamoeba histolytica, Trichomonas, and anaerobic bacteria. Simethicone (10mg/5mL) is an anti-foaming/anti-flatulence agent that reduces gas-related bloating, cramping, and discomfort commonly associated with gastrointestinal infections.

Indications

Paediatric and adult gastrointestinal infections with mixed aerobic-anaerobic aetiology: acute gastroenteritis, amoebic dysentery, Giardiasis, Shigellosis, traveller's diarrhoea, and infective diarrhoea with bloating. The simethicone component addresses the symptomatic gas and bloating that accompanies many enteric infections, providing relief alongside antimicrobial treatment.

Dosage & Administration

Dosage and administration should be as prescribed by a qualified doctor or medical professional. Do not self-medicate. Always follow your physician's instructions regarding dose, frequency and duration of treatment.

Why OFLOFT™ MS?

Acute gastroenteritis and infective diarrhoea with mixed pathogen involvement are among the most common reasons for paediatric consultation in India. A single suspension covering aerobic gram-negative organisms (ofloxacin), anaerobes and protozoa (metronidazole), and gas symptoms (simethicone) reduces the prescription burden to a single product and improves compliance versus multiple separate medicines.

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Disclaimer: To be used under medical supervision only. Not intended for general public promotion. This content is meant for registered healthcare professionals only.

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