SECZYME PLUS

SECZYME PLUS is a digestive enzyme-vitamin combination syrup addressing two interrelated aspects of digestive function — enzymatic protein digestion and B-vitamin-dependent metabolic support of GI function.

Papain (60mg per 5mL) is a cysteine protease enzyme derived from the latex of Carica papaya. It catalyses the hydrolysis of peptide bonds in proteins, breaking polypeptide chains into smaller peptides and amino acids. Papain's proteolytic activity is active across a broad pH range (3.0–10.0) — including the gastric (pH 1.5–3.5) and intestinal (pH 6–8) environments — making it effective throughout the GI tract. In conditions of pancreatic exocrine insufficiency or age-related enzyme decline, supplemental papain compensates for reduced endogenous protease activity, improving protein digestion and absorption. Papain also has anti-inflammatory properties — reducing intestinal mucosal inflammation — and mucolytic activity — thinning intestinal mucus to improve nutrient contact with the absorptive epithelium.

Pyridoxine HCl (Vitamin B6, 0.75mg per 5mL) is an essential water-soluble vitamin serving as a cofactor for over 100 enzyme reactions, predominantly in amino acid metabolism. In the GI context, B6 is required for transamination reactions that metabolise the amino acids released by papain's proteolytic activity — ensuring that digested proteins are efficiently metabolised rather than lost. B6 deficiency causes altered GI motility and nausea, and supplementation in deficiency states improves appetite and digestive comfort.

Thiamine Mononitrate (Vitamin B1, 1mg per 5mL) is required for carbohydrate metabolism — specifically as a cofactor for pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase in the Krebs cycle. B1 deficiency impairs GI motility (causing nausea, vomiting, and anorexia) and reduces intestinal peristaltic efficiency. Thiamine supplementation in deficiency states restores normal GI motility and appetite.

SECZYME PLUS is indicated for digestive insufficiency, nutritional support in GI disease, and conditions where improved protein digestion and B-vitamin status are clinically beneficial.

Digestive Enzyme Deficiency: Protein maldigestion in conditions of reduced gastric acid secretion (achlorhydria, PPI use), pancreatic insufficiency, and age-related enzyme decline.

Paediatric Appetite and Growth: Children with poor appetite, slow weight gain, or selective eating — papain improves protein digestibility from dietary sources while B-vitamins support the metabolic processing of absorbed nutrients.

Post-Illness Nutritional Recovery: Following acute GI illness (gastroenteritis, hepatitis) where digestive enzyme capacity is temporarily reduced and B-vitamin depletion occurs.

Protein Malnutrition: Supplementary enzyme support to maximise protein absorption from a protein-adequate diet in malnourished children and adults.

Irritable Bowel Syndrome with Bloating: Papain's protein digestion enhancement reduces incompletely digested protein that undergoes fermentation in the colon, reducing gas production and bloating.

Dosage and administration should be as prescribed by a qualified doctor or medical professional. Do not self-medicate. Always follow your physician's instructions regarding dose, frequency and duration of treatment.